Benzyl Bromide → 3-benzylthiophene

HRID 234428Notes

Reaction equation

HRID 234428 reaction equation
[S:1]1[CH:5]=[CH:4][C:3](B(O)O)=[CH:2]1.[CH2:9](Br)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:9]([C:3]1[CH:4]=[CH:5][S:1][CH:2]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 581760Thiophene-3-boronic acid

Product 1

HCID 104874713-benzylthiopheneYield 74%

Procedure

3-benzylthiophene was prepared in the same manner as described in Example 32C using 3-thienylboronic acid and benzyl bromide, 74% yield.

Sources & evidence

ORD record
ord-87aa33f3079246289780b918252b05d3
Source dataset
uspto-grants-1997_01
Patent number
US05594021

Reaction notes

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