Triphenylphosphine → 6-{1-[6-(1-Ethoxy-vinyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-ethyl}-5,7-difluoro-quinoline
Reaction equation
[CH2:25]([Sn:26]([CH2:27][CH2:28][CH2:29][CH3:35])([C:30](=[CH2:31])[O:32][CH2:33][CH3:34])[CH2:36][CH2:37][CH2:38][CH3:39])[CH2:40][CH2:41][CH3:42].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8]([CH:11]([CH3:12])[c:13]1[c:14]([F:24])[c:15]3[cH:16][cH:17][cH:18][n:19][c:20]3[cH:21][c:22]1[F:23])[n:9][n:10]2.[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[Pd:49]([Cl:50])[Cl:51].[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1.[c:71]1([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[cH:85][cH:86][cH:87][cH:88][cH:89]1>>[c:2]1([C:30](=[CH2:31])[O:32][CH2:33][CH3:34])[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8]([CH:11]([CH3:12])[c:13]1[c:14]([F:24])[c:15]3[cH:16][cH:17][cH:18][n:19][c:20]3[cH:21][c:22]1[F:23])[n:9][n:10]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-67db78228d8341448b3c0467f9abce8f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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