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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2344366Generated: October 25, 2026

Dimethylformamide → 3-cyclopentyl-N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)pyrazin-2-yl]-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]propanamide

https://huagongshe.com/reaction/2344366

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
Reactant2,6-LutidineHCID 7937—
ReactantOxalyl chlorideHCID 65578—
Reactant5-(2,2-Dimethyl-1,3-dioxolan-4-yl)pyrazin-2-amineHCID 21897304—
Reactant3-cyclopentyl-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]propanoic acidHCID 70945342—
Product3-cyclopentyl-N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)pyrazin-2-yl]-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]propanamideHCID 70945614—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-e472aafef425421fa88b3b9ba57ecd2b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)