Dimethylformamide → 3-cyclopentyl-N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)pyrazin-2-yl]-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]propanamide
Reaction equation
[CH2:53]([Cl:54])[Cl:55].[CH3:31][C:32]1([CH3:44])[O:33][CH2:34][CH:35]([c:37]2[n:38][cH:39][c:40]([NH2:43])[n:41][cH:42]2)[O:36]1.[CH3:56][N:57]([CH3:58])[CH:59]=[O:60].[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[N:11]2[C:12](=[O:24])[c:13]3[cH:14][cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[c:18]3[CH2:19]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:25][C:26]([C:27]([Cl:28])=[O:29])=[O:30].[n:45]1[c:46]([CH3:47])[cH:48][cH:49][cH:50][c:51]1[CH3:52]>>[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[NH:43][c:40]2[cH:39][n:38][c:37]([CH:35]3[CH2:34][O:33][C:32]([CH3:31])([CH3:44])[O:36]3)[cH:42][n:41]2)[N:11]2[C:12](=[O:24])[c:13]3[cH:14][cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[c:18]3[CH2:19]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e472aafef425421fa88b3b9ba57ecd2b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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