Dichloromethane → Tert-butyl 5-[[2-[3-[[2-methyl-3-[(2-methylpropan-2-yl)oxy]-3-oxopropanoyl]amino]phenyl]quinazolin-4-yl]amino]indazole-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH:8]([C:9](=[O:10])[OH:11])[CH3:12].[CH:46]([N:47]([CH2:48][CH3:49])[CH:50]([CH3:51])[CH3:52])([CH3:53])[CH3:54].[Cl:89][CH2:90][Cl:91].[NH2:55][c:56]1[cH:57][c:58](-[c:62]2[n:63][c:64]3[cH:65][cH:66][cH:67][cH:68][c:69]3[c:70]([NH:72][c:73]3[cH:74][c:75]4[cH:76][n:77][n:78]([C:82](=[O:83])[O:84][C:85]([CH3:86])([CH3:87])[CH3:88])[c:79]4[cH:80][cH:81]3)[n:71]2)[cH:59][cH:60][cH:61]1.[P-:13]([F:14])([F:15])([F:16])([F:17])([F:18])[F:19].[n:20]1([O:21][P+:22]([N:23]2[CH2:24][CH2:25][CH2:26][CH2:27]2)([N:28]2[CH2:29][CH2:30][CH2:31][CH2:32]2)[N:33]2[CH2:34][CH2:35][CH2:36][CH2:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH:8]([C:9](=[O:11])[NH:55][c:56]1[cH:57][c:58](-[c:62]2[n:63][c:64]3[cH:65][cH:66][cH:67][cH:68][c:69]3[c:70]([NH:72][c:73]3[cH:74][c:75]4[cH:76][n:77][n:78]([C:82](=[O:83])[O:84][C:85]([CH3:86])([CH3:87])[CH3:88])[c:79]4[cH:80][cH:81]3)[n:71]2)[cH:59][cH:60][cH:61]1)[CH3:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-da76e3f3b9764a1f880395ec6c4dc490
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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