1-Butanol → 5-bromo-2-N-[4-(4-methylpiperazin-1-yl)phenyl]-4-N-phenylpyrimidine-2,4-diamine
Reaction equation
[CH2:33]([OH:34])[CH2:35][CH2:36][CH3:37].[CH3:2][N:3]1[CH2:4][CH2:5][N:6]([c:9]2[cH:10][cH:11][c:12]([NH2:13])[cH:14][cH:15]2)[CH2:7][CH2:8]1.[CH3:31][OH:32].[ClH:1].[NH:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[c:23]1[n:24][c:25]([Cl:30])[n:26][cH:27][c:28]1[Br:29]>>[CH3:2][N:3]1[CH2:4][CH2:5][N:6]([c:9]2[cH:10][cH:11][c:12]([NH:13][c:25]3[n:24][c:23]([NH:16][c:17]4[cH:18][cH:19][cH:20][cH:21][cH:22]4)[c:28]([Br:29])[cH:27][n:26]3)[cH:14][cH:15]2)[CH2:7][CH2:8]1Participants
6
Sources & evidence
- ORD record
- ord-e9c583268dd14796ba9d5025880fe8ac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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