Methanol → 5-Fluoro-6-methyl-1-[1-(tetrahydropyran-4-yl)-piperidin-4-yl]-1,3-dihydrobenzimidazol-2-one
Reaction equation
[C:26]([BH3-:27])#[N:28].[CH3:30][OH:31].[CH3:32][CH:33]([CH3:34])[O-:35].[CH3:36][CH:37]([CH3:38])[O-:39].[CH3:40][CH:41]([CH3:42])[O-:43].[CH3:44][CH:45]([CH3:46])[O-:47].[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:16][c:17]1[CH3:18].[Na+:29].[O:19]1[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]1.[Ti+4:48]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH2:11][CH2:12][N:13]([CH:22]4[CH2:21][CH2:20][O:19][CH2:24][CH2:23]4)[CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:16][c:17]1[CH3:18]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9be6574891a344e9b6362bf566f44fd7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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