2,4-Dimethoxybenzenesulfonyl chloride → HCID 19076474, compound

HRID 234513Notes

Reaction equation

[CH2:1]([O:3][C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][C:8](=[O:13])[C:7]2([N:20]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[NH:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH3:2].[CH3:32][O:33][C:34]1[CH:39]=[C:38]([O:40][CH3:41])[CH:37]=[CH:36][C:35]=1[S:42](Cl)(=[O:44])=[O:43]>>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([S:42]([C:35]1[CH:36]=[CH:37][C:38]([O:40][CH3:41])=[CH:39][C:34]=1[O:33][CH3:32])(=[O:44])=[O:43])[C:8](=[O:13])[C:7]2([N:20]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[NH:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH3:2]

Participants

Reactant 2

HCID 27346262,4-Dimethoxybenzenesulfonyl chloride

HCID 19076611HCID 19076611, compound

Product 1

HCID 19076474HCID 19076474, compound

Procedure

This compound is prepared according to the procedure described in EXAMPLE 1 from 0.500 g of 5-ethoxy-3-(2-ethoxycarbonyl-1-ethoxycarbonylhydrazino)-1,3-dihydro-3-phenylindol-2-one and 0.280 g of 2,4-dimethoxybenzenesulfonyl chloride. The expected product is obtained after crystallization from a DCM/iso ether mixture. m=0.383 g. M.p.=228°-229° C.

Workup

customThis compound is prepared

Sources & evidence

ORD record: ord-7b951e58becb46c1833cff2ea6c8b40c
Source dataset: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05594023

Reaction notes

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