Tetrahydrofuran → Nepafenac

HRID 2345201Notes

Reaction equation

[NH2:1][c:2]1[c:3]([CH:16]([C:17](=[O:18])[NH2:19])[S:20][CH3:21])[cH:4][cH:5][cH:6][c:7]1[C:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)=[O:15].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1>>[NH2:1][c:2]1[c:3]([CH2:16][C:17](=[O:18])[NH2:19])[cH:4][cH:5][cH:6][c:7]1[C:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)=[O:15]

Participants

Reactant 2

HCID 8028Tetrahydrofuran

HCID 156347272-(2-Amino-3-benzoylphenyl)-2-(methylsulfanyl)acetamide

Product 1

HCID 151075Nepafenac

Sources & evidence

ORD record: ord-9456eb2cf88c494d9599ea756274c269
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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