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HRID234526

反应详情

EQUATION

反应方程式

HRID 234526 的结构方程式

REACTANTS

反应物

3
结构：COc1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1
HCID87452

4-Methoxy-2-nitrobenzenesulphonyl chloride

C7H6ClNO5S

结构：NC1(c2ccccc2Cl)C(=O)Nc2ccc(Cl)cc21
HCID19076376

未命名化合物

结构：CCCCCC.CCOC(C)=O
HCID21226206

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(S(=O)(=O)N2C(=O)C(N)(c3ccccc3Cl)c3cc(Cl)ccc32)c([N+](=O)[O-])c1
HCID19076369

未命名化合物

收率 81.1%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

This compound is prepared according to the procedure described in EXAMPLE 1 from 2 g of 3-amino-5-chloro-3-(2-chlorophenyl)-1,3-dihydroindol-2-one and 1.71 g of 4-methoxy-2-nitrobenzenesulfonyl chloride. Chromatography on silica using a DCM/hexane mixture (80/20; v/v) and then DCM as the eluent gives 2.8 g of the expected product after crystallization from a DCM/iso ether mixture. M.p.=192°-195° C.

WORKUP

后处理

  1. customThis compound is prepared