Methanol → 1-tert-Butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

HRID 2345595Notes

Reaction equation

HRID 2345595 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[OH:16])[CH2:10][C:11](=[O:13])[CH2:12]1.[CH3:17][OH:18].[CH3:19][Si:20]([CH:21]=[N+:22]=[N-:23])([CH3:24])[CH3:25].[CH3:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:19])[CH2:10][C:11](=[O:13])[CH2:12]1

Participants

5

Reactant 4

HCID 887MethanolHCID 1140TolueneHCID 167693TrimethylsilyldiazomethaneHCID 41506451-((Tert-butoxy)carbonyl)-4-oxopyrrolidine-2-carboxylic acid

Product 1

HCID 42518531-tert-Butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-c8f842be2c1f40718c1f93c2700ea852
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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