Acetate → 2-[4-(Pyrrolidin-1-yl)phenyl]acetic acid

HRID 2345644Notes

Reaction equation

HRID 2345644 reaction equation
[Br:14][c:15]1[cH:16][cH:17][c:18]([CH2:21][C:22](=[O:23])[OH:24])[cH:19][cH:20]1.[C:30]([O-:31])(=[O:32])[CH3:33].[C:35]([O-:36])(=[O:37])[CH3:38].[CH2:25]1[CH2:26][CH2:27][NH:28][CH2:29]1.[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[CH3:8][C:9]([CH3:10])([O-:11])[CH3:12].[Na+:13].[OH2:39].[Pd+2:34]>>[c:15]1([N:28]2[CH2:27][CH2:26][CH2:25][CH2:29]2)[cH:16][cH:17][c:18]([CH2:21][C:22](=[O:23])[OH:24])[cH:19][cH:20]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 923Sodium ionHCID 962WaterHCID 1140TolueneHCID 31268PyrrolidineHCID 74654Benzeneacetic acid, 4-bromo-HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 45749132-Methylpropan-2-olate

Product 1

HCID 141545872-[4-(Pyrrolidin-1-yl)phenyl]acetic acid

Sources & evidence

ORD record
ord-971871e94f544bc58038b352c5f1f6e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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