Dichloromethane → Tert-butyl {4-[(7-bromo-3-nitroquinolin-4-ylamino)methyl]benzyl}carbamate

HRID 2345823Notes

Reaction equation

HRID 2345823 reaction equation
[Br:18][c:19]1[cH:20][cH:21][c:22]2[c:23]([Cl:32])[c:24]([N+:29](=[O:30])[O-:31])[cH:25][n:26][c:27]2[cH:28]1.[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([CH2:16][NH2:17])[cH:14][cH:15]1.[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[Cl:40][CH2:41][Cl:42]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([CH2:16][NH:17][c:23]2[c:22]3[cH:21][cH:20][c:19]([Br:18])[cH:28][c:27]3[n:26][cH:25][c:24]2[N+:29](=[O:30])[O-:31])[cH:14][cH:15]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 3354775tert-butyl N-{[4-(aminomethyl)phenyl]methyl}carbamateHCID 219843617-Bromo-4-chloro-3-nitroquinoline

Product 1

HCID 21984421Tert-butyl {4-[(7-bromo-3-nitroquinolin-4-ylamino)methyl]benzyl}carbamate

Sources & evidence

ORD record
ord-2f0df698ea7a4cacacfb6854fb09ac88
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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