Dichloromethane → 3-[(4-Bromo-2,6-dimethylphenoxy)methyl]piperidine

HRID 2345845Notes

Reaction equation

HRID 2345845 reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH:17]([CH2:21][O:22][c:23]2[c:24]([CH3:31])[cH:25][c:26]([Br:30])[cH:27][c:28]2[CH3:29])[CH2:18][CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[Cl:32][CH2:33][Cl:34].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH:17]([CH2:21][O:22][c:23]2[c:24]([CH3:31])[cH:25][c:26]([Br:30])[cH:27][c:28]2[CH3:29])[CH2:18][CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21184191Tert-butyl 3-[(4-bromo-2,6-dimethylphenoxy)methyl]piperidine-1-carboxylate

Product 1

HCID 158952203-[(4-Bromo-2,6-dimethylphenoxy)methyl]piperidine

Sources & evidence

ORD record
ord-3277de48e0ce42deafff9c36ddc6b462
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…