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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2346120Generated: November 2, 2026

Tetrahydrofuran → 3-(2-Fluoro-4-iodophenyl)-1-(1-(2-(tert-butyldimethylsilyloxy)ethyl)cyclopropylsulfonyl)-4-fluoro-8-methyl-1H-imidazo[4,5-g]quinazolin-2(3H)-one

https://huagongshe.com/reaction/2346120

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactant1-[2-(Tert-butyldimethylsilanyloxy)ethyl]-cyclopropanesulfonyl chlorideHCID 59386326—
Reactant3-(2-Fluoro-4-iodophenyl)-4-fluoro-8-methyl-1H-imidazo[4,5-g]quinazolin-2(3H)-oneHCID 59519492—
Product3-(2-Fluoro-4-iodophenyl)-1-(1-(2-(tert-butyldimethylsilyloxy)ethyl)cyclopropylsulfonyl)-4-fluoro-8-methyl-1H-imidazo[4,5-g]quinazolin-2(3H)-oneHCID 59519481—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-c2283230d084452b96829bb66d808686
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)