Diethyl Ether → 3-Dibenzylaminocyclohexylmethanol

HRID 2346298Notes

Reaction equation

HRID 2346298 reaction equation
[Al+3:58].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]1[CH2:10][CH:11]([C:15](=[O:16])[O:17][CH3:18])[CH2:12][CH2:13][CH2:14]1)[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[CH2:26]([N:27]([CH2:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[CH:35]1[CH2:36][CH2:37][CH2:38][CH:39]([C:40]([O:41][CH2:42][c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)=[O:49])[CH2:50]1)[c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1.[CH3:63][CH2:64][O:65][CH2:66][CH3:67].[H-:57].[H-:60].[H-:61].[H-:62].[Li+:59]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]1[CH2:10][CH:11]([CH2:15][OH:16])[CH2:12][CH2:13][CH2:14]1)[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1

Participants

7

Reactant 6

HCID 3283Diethyl EtherHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 57882728Methyl 3-dibenzylaminocyclohexanoateHCID 57882731Benzyl 3-dibenzylaminocyclohexanoate

Product 1

HCID 596592093-Dibenzylaminocyclohexylmethanol

Sources & evidence

ORD record
ord-59a62c5389d942d49610a299b7074044
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…