Hydroxide → N4-(4-tert-butylphenyl)-N2-(2-carboxybenzofuran-5-yl)-5-fluoro-2,4-pyrimidinediamine

HRID 2346491Notes

Reaction equation

HRID 2346491 reaction equation
[C:3]([CH3:4])([CH3:5])([CH3:6])[c:7]1[cH:8][cH:9][c:10]([NH:13][c:14]2[n:15][c:16]([NH:21][c:22]3[cH:23][cH:24][c:25]4[c:26]([cH:27][c:28]([C:30](=[O:31])[O:32][CH3:33])[o:29]4)[cH:34]3)[n:17][cH:18][c:19]2[F:20])[cH:11][cH:12]1.[Li+:2].[OH-:1]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[c:7]1[cH:8][cH:9][c:10]([NH:13][c:14]2[n:15][c:16]([NH:21][c:22]3[cH:23][cH:24][c:25]4[c:26]([cH:27][c:28]([C:30](=[O:31])[OH:32])[o:29]4)[cH:34]3)[n:17][cH:18][c:19]2[F:20])[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 961HydroxideHCID 28486Lithium ionHCID 22060304N4-(4-tert-butylphenyl)-5-fluoro-N2-(2-methoxycarbonylbenzofuran-5-yl)-2,4-pyrimidinediamine

Product 1

HCID 22060444N4-(4-tert-butylphenyl)-N2-(2-carboxybenzofuran-5-yl)-5-fluoro-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-acafae27fd4e4202b45941a06633f38e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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