Water → tert-Butyl 4-[(6-bromo-2-{[1-({[tert-butyl(dimethyl)silyl]oxy}methyl)cyclobutyl]methyl}-1-oxo-1,2-dihydroisoquinolin-4-yl)methyl]piperazine-1-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH2:13][N:14]3[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]3)[cH:6][nH:7][c:8](=[O:12])[c:9]2[cH:10][cH:11]1.[C:27](=[O:28])([O-:29])[O-:30].[CH3:33][S:34]([O:35][CH2:38][C:39]1([CH2:43][O:44][Si:45]([CH3:46])([CH3:47])[C:48]([CH3:49])([CH3:50])[CH3:51])[CH2:40][CH2:41][CH2:42]1)(=[O:36])=[O:37].[Cs+:31].[Cs+:32].[O:52]=[CH:53][N:54]([CH3:55])[CH3:56].[OH2:57]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH2:13][N:14]3[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]3)[cH:6][n:7]([CH2:38][C:39]3([CH2:43][O:44][Si:45]([CH3:46])([CH3:47])[C:48]([CH3:49])([CH3:50])[CH3:51])[CH2:40][CH2:41][CH2:42]3)[c:8](=[O:12])[c:9]2[cH:10][cH:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f2cec2a8fa524546815d38c7b2755dda
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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