Water → 4-(4-fluorobenzyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine 6-oxide

HRID 2346701Notes

Reaction equation

HRID 2346701 reaction equation
[Cl:44][CH2:45][Cl:46].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[c:8]3[c:9]([n:10][c:11]([NH:13][c:14]4[cH:15][cH:16][c:17](-[n:20]5[c:21]([CH3:25])[n:22][cH:23][cH:24]5)[cH:18][cH:19]4)[n:12]2)[CH2:26][CH2:27][S:28][CH2:29]3)[cH:30][cH:31]1.[OH2:43].[OH:32][O:33][C:34]([c:35]1[cH:36][c:37]([Cl:38])[cH:39][cH:40][cH:41]1)=[O:42]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[c:8]3[c:9]([n:10][c:11]([NH:13][c:14]4[cH:15][cH:16][c:17](-[n:20]5[c:21]([CH3:25])[n:22][cH:23][cH:24]5)[cH:18][cH:19]4)[n:12]2)[CH2:26][CH2:27][S:28](=[O:32])[CH2:29]3)[cH:30][cH:31]1

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 70297m-Chloroperbenzoic acidHCID 593337504-(4-Fluorobenzyl)-N-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine

Product 1

HCID 461992744-(4-fluorobenzyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine 6-oxide

Sources & evidence

ORD record
ord-19002cb26f7f42169192c2e78b006c5d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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