4-Nitrophenyl chloroformate → 3-[4-[2-(2,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yloxycarbonylamino)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxybutyl]phenoxy]propyl (4-nitrophenyl) carbonate

HRID 2347330Notes

Reaction equation

HRID 2347330 reaction equation
[Cl:46][C:47](=[O:48])[O:49][c:50]1[cH:51][cH:52][c:53]([N+:56](=[O:57])[O-:58])[cH:54][cH:55]1.[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([S:10](=[O:11])(=[O:12])[N:13]([CH2:14][CH:15]([CH:16]([CH2:17][c:18]1[cH:19][cH:20][c:21]([O:24][CH2:25][CH2:26][CH2:27][OH:28])[cH:22][cH:23]1)[NH:29][C:30]([O:31][CH:32]1[CH2:33][O:34][CH:35]3[O:36][CH2:37][CH2:38][CH:39]13)=[O:40])[OH:41])[CH2:42][CH:43]([CH3:44])[CH3:45])[cH:9]2>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([S:10](=[O:11])(=[O:12])[N:13]([CH2:14][CH:15]([CH:16]([CH2:17][c:18]1[cH:19][cH:20][c:21]([O:24][CH2:25][CH2:26][CH2:27][O:28][C:47](=[O:48])[O:49][c:50]3[cH:51][cH:52][c:53]([N+:56](=[O:57])[O-:58])[cH:54][cH:55]3)[cH:22][cH:23]1)[NH:29][C:30]([O:31][CH:32]1[CH2:33][O:34][CH:35]3[O:36][CH2:37][CH2:38][CH:39]13)=[O:40])[OH:41])[CH2:42][CH:43]([CH3:44])[CH3:45])[cH:9]2

Participants

3

Reactant 2

HCID 821294-Nitrophenyl chloroformateHCID 207742912,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl N-[4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-(3-hydroxypropoxy)phenyl]butan-2-yl]carbamate

Product 1

HCID 224998053-[4-[2-(2,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yloxycarbonylamino)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxybutyl]phenoxy]propyl (4-nitrophenyl) carbonate

Sources & evidence

ORD record
ord-91ffc6a714ba45129319ff85d67b49c4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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