Tetrahydrofuran → N-[4-(2-chlorophenyl)-2-ethylthieno[2,3-b]pyridin-5-yl]-N'-(2,4-difluorophenyl)urea
Reaction equation
[F:20][c:21]1[c:22]([N:28]=[C:29]=[O:30])[cH:23][cH:24][c:25]([F:27])[cH:26]1.[NH2:1][c:2]1[c:3](-[c:13]2[c:14]([Cl:19])[cH:15][cH:16][cH:17][cH:18]2)[c:4]2[c:5]([n:6][cH:7]1)[s:8][c:9]([CH2:11][CH3:12])[cH:10]2.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[NH:1]([c:2]1[c:3](-[c:13]2[c:14]([Cl:19])[cH:15][cH:16][cH:17][cH:18]2)[c:4]2[c:5]([n:6][cH:7]1)[s:8][c:9]([CH2:11][CH3:12])[cH:10]2)[C:29]([NH:28][c:22]1[c:21]([F:20])[cH:26][c:25]([F:27])[cH:24][cH:23]1)=[O:30]Participants
4
Sources & evidence
- ORD record
- ord-2da41b1f4f8d4b26b6c84f6bc4685b3e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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