Dichloromethane → 6-tert-butyl-8-fluoro-2-(2-(hydroxymethyl)-3-(1-methyl-5-(5-(1-(methylsulfonyl)-piperidin-4-yl)pyridin-2-ylamino)-6-oxo-1,6-dihydropyridazin-3-yl)phenyl)phthalazin-1(2H)-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[cH:8][n:9][n:10](-[c:17]3[c:18]([CH2:44][OH:45])[c:19](-[c:23]4[n:24][n:25]([CH3:43])[c:26](=[O:42])[c:27]([NH:29][c:30]5[n:31][cH:32][c:33]([CH:36]6[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]6)[cH:34][cH:35]5)[cH:28]4)[cH:20][cH:21][cH:22]3)[c:11](=[O:16])[c:12]2[c:13]([F:15])[cH:14]1.[CH3:55][S:56]([Cl:57])(=[O:58])=[O:59].[CH:46]([N:47]([CH2:48][CH3:49])[CH:50]([CH3:51])[CH3:52])([CH3:53])[CH3:54].[Cl:60][CH2:61][Cl:62]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[cH:8][n:9][n:10](-[c:17]3[c:18]([CH2:44][OH:45])[c:19](-[c:23]4[n:24][n:25]([CH3:43])[c:26](=[O:42])[c:27]([NH:29][c:30]5[n:31][cH:32][c:33]([CH:36]6[CH2:37][CH2:38][N:39]([S:56]([CH3:55])(=[O:58])=[O:59])[CH2:40][CH2:41]6)[cH:34][cH:35]5)[cH:28]4)[cH:20][cH:21][cH:22]3)[c:11](=[O:16])[c:12]2[c:13]([F:15])[cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2c0c83f1a7414f9897d09650578142bb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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