HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 1-[4-(3-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1-yl]-2-(6-hydroxy-naphth-2-yl)ethane hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 1-[4-(3-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1-yl]-2-(6-methoxy-naphth-2-yl)ethane hydrochloride | HCID 19962086 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 1-[4-(3-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1-yl]-2-(6-hydroxy-naphth-2-yl)ethane hydrobromide | HCID 19962090 | — |
Reaction Steps
A mixture of 1-[4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1-yl]-2-(6-methoxy-naphth-2-yl)ethane hydrochloride (0.6 g, 0.0013 mol)(obtained as described in Example 3) and 33% HBr in acetic acid (20 ml) is refluxed for 4 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05596101 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-23664479d5a24ab191945229f32de959 |
| Source note | uspto-grants-1997_01 |