Methanol → 1-[1-[4-[[3-Bromo-5-(trifluoromethyl)benzoyl]-methylamino]-3-(4-fluorophenyl)butyl]azetidin-3-yl]piperidine-4-carboxamide
Reaction equation
[C:63]([BH3-:64])#[N:65].[CH2:67]([Cl:68])[Cl:69].[CH3:56][CH2:57][N:58]([CH2:59][CH3:60])[CH2:61][CH3:62].[CH3:70][OH:71].[N:1]1([C:5](=[O:6])[CH:7]2[CH2:8][CH2:9][N:10]([CH:13]3[CH2:14][N:15]([CH2:17][CH2:18][CH:19]([CH2:20][N:21]([C:22]([c:23]4[cH:24][c:25]([Br:33])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]4)=[O:34])[CH3:35])[c:36]4[cH:37][cH:38][c:39]([F:42])[cH:40][cH:41]4)[CH2:16]3)[CH2:11][CH2:12]2)[CH2:2][CH2:3][CH2:4]1.[NH:43]1[CH2:44][CH:45]([N:46]2[CH2:47][CH2:48][CH:49]([C:50]([NH2:51])=[O:52])[CH2:53][CH2:54]2)[CH2:55]1.[Na+:66]>>[NH2:1][C:5](=[O:6])[CH:7]1[CH2:8][CH2:9][N:10]([CH:13]2[CH2:14][N:15]([CH2:17][CH2:18][CH:19]([CH2:20][N:21]([C:22]([c:23]3[cH:24][c:25]([Br:33])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]3)=[O:34])[CH3:35])[c:36]3[cH:37][cH:38][c:39]([F:42])[cH:40][cH:41]3)[CH2:16]2)[CH2:11][CH2:12]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5bc2e43fa17c4f8c8c6a90405d46e71e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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