Potassium Carbonate → HCID 4647665, compound

HRID 23483Notes

Reaction equation

HRID 23483 reaction equation
[C:1]([C:5]1[CH:6]=[CH:7][C:8]([N+:18]([O-:20])=[O:19])=[C:9]([NH:11]C(=O)C(F)(F)F)[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CO>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([N+:18]([O-:20])=[O:19])=[C:9]([NH2:11])[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 22572832N-(5-tert-Butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide

Product 1

HCID 4647665HCID 4647665, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound was prepared as outlined in Example PP-1 from N-(5-tert-butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide (prepared in Example OO-2; 248 g, 855 mmol), MeOH (500 mL), and 7% aqueous potassium carbonate solution. The crude product was used without any purification. MS(APCI): 195 (M+H).

Workup

  1. customThe crude product was used without any purification

Sources & evidence

ORD record
ord-c77133d2549b45b9a0778b01884be175
Source dataset
uspto-grants-2005_02
Patent number
US06852711B2

Reaction notes

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