Sodium ion → Tert-butyl 4-(4-amino-7-iodofuro[3,2-c]pyridin-3-yl)-2-methoxyphenylcarbamate

HRID 2348441Notes

Reaction equation

HRID 2348441 reaction equation
[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[I:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[NH2:9][c:10]1[n:11][cH:12][cH:13][c:14]2[c:15]1[c:16](-[c:19]1[cH:20][c:21]([O:33][CH3:34])[c:22]([NH:25][C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[cH:23][cH:24]1)[cH:17][o:18]2.[Na+:40].[Na+:41].[S:35]([O-:36])([O-:37])(=[O:38])=[S:39]>>[I:1][c:13]1[cH:12][n:11][c:10]([NH2:9])[c:15]2[c:14]1[o:18][cH:17][c:16]2-[c:19]1[cH:20][c:21]([O:33][CH3:34])[c:22]([NH:25][C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[cH:23][cH:24]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 1084Thiosulfate ionHCID 6228DimethylformamideHCID 120273N-IodosuccinimideHCID 18451465Tert-butyl 4-(4-aminofuro[3,2-c]pyridin-3-yl)-2-methoxyphenylcarbamate

Product 1

HCID 18451460Tert-butyl 4-(4-amino-7-iodofuro[3,2-c]pyridin-3-yl)-2-methoxyphenylcarbamate

Sources & evidence

ORD record
ord-f1be6aff5e194fa1b02168c6d9f63948
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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