Sodium ion → 2-[4-(3-chloro-2-pyridinyl)-3,6-dihydro-2H-pyridin-1-yl]-N-(2-methylphenyl)acetamide

HRID 2348709Notes

Reaction equation

[CH3:14][c:15]1[c:16]([NH:21][C:22]([CH2:23][Cl:24])=[O:25])[cH:17][cH:18][cH:19][cH:20]1.[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:1][c:2]1[c:3]([C:8]2=[CH:13][CH2:12][NH:11][CH2:10][CH2:9]2)[n:4][cH:5][cH:6][cH:7]1.[Na+:26].[Na+:27].[O-:28][C:29](=[O:30])[O-:31].[OH2:32]>>[Cl:1][c:2]1[c:3]([C:8]2=[CH:13][CH2:12][N:11]([CH2:23][C:22]([NH:21][c:16]3[c:15]([CH3:14])[cH:20][cH:19][cH:18][cH:17]3)=[O:25])[CH2:10][CH2:9]2)[n:4][cH:5][cH:6][cH:7]1

Participants

Reactant 6

HCID 923Sodium ion2×

HCID 962Water

HCID 6228Dimethylformamide

HCID 19660Carbonate Ion

HCID 101479Acetamide, 2-chloro-N-(2-methylphenyl)-

HCID 688738073-Chloro-2-(1,2,3,6-tetrahydropyridin-4-yl)pyridine

Product 1

HCID 688748782-[4-(3-chloro-2-pyridinyl)-3,6-dihydro-2H-pyridin-1-yl]-N-(2-methylphenyl)acetamide

Sources & evidence

ORD record: ord-94bd6eb25684412d9dd62cbfcc73fb20
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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