Acetonitrile → 5-(5-Amino-6-phenoxypyrimidin-4-yl)pent-2-en-4-yn-1-ol

HRID 2348890Notes

Reaction equation

HRID 2348890 reaction equation
[CH2:16]([CH:17]=[CH:18][C:19]#[CH:20])[OH:21].[CH3:22][C:23]#[N:24].[Cu:25][I:26].[I:1][c:2]1[n:3][cH:4][n:5][c:6]([O:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[c:7]1[NH2:8]>>[c:2]1([C:20]#[C:19][CH:18]=[CH:17][CH2:16][OH:21])[n:3][cH:4][n:5][c:6]([O:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[c:7]1[NH2:8]

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 977582-Penten-4-yn-1-olHCID 860847854-Iodo-6-phenoxy-5-pyrimidinamine

Product 1

HCID 860847935-(5-Amino-6-phenoxypyrimidin-4-yl)pent-2-en-4-yn-1-ol

Sources & evidence

ORD record
ord-d3b5de37552343689d720ed61a6ff1a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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