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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 234938Generated: October 27, 2026

2,5-Dichlorobenzylic alcohol → 2,4-Diamino-5-(2,5-dichlorophenyl)-6-methylpyrimidine

https://huagongshe.com/reaction/234938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dichlorobenzylic alcoholHCID 118604—
Reactant2,4-Diamino-6-methyl-5-(2,3,5-trichlorophenyl)pyrimidineHCID 11551232—
SolventChloroform methanolHCID 21584188—
Product2,4-Diamino-5-(2,5-dichlorophenyl)-6-methylpyrimidineHCID 19705116—

Reaction Steps

This compound was made in an analogous manner to the compound of Example 6 from 2,5-dichlorobenzylalcohol (Lancaster Synthesis). Mp. 226°-228° C.: TLC (SiO2 :CHCl3 /MeOH, 9:1) Rf=0.24.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05597827
Source datasetuspto-grants-1997_01
ORD IDord-9364716df0394e289c9c24426411d130
Source noteuspto-grants-1997_01