Water → N-[4-(6-cyano-7-oxiranylmethoxyquinolin-4-yloxy)-2-fluorophenyl]-N'-(4-fluorophenyl)urea
Reaction equation
[CH3:1][N:2]([CH3:3])[CH:4]=[O:5].[F:6][c:7]1[cH:8][cH:9][c:10]([N:13]=[C:14]=[O:15])[cH:11][cH:12]1.[NH2:16][c:17]1[c:18]([F:41])[cH:19][c:20]([O:21][c:22]2[cH:23][cH:24][n:25][c:26]3[cH:27][c:28]([O:34][CH2:35][CH:36]4[O:37][CH2:38]4)[c:29]([C:32]#[N:33])[cH:30][c:31]23)[cH:39][cH:40]1.[OH2:42]>>[F:6][c:7]1[cH:8][cH:9][c:10]([NH:13][C:14](=[O:15])[NH:16][c:17]2[c:18]([F:41])[cH:19][c:20]([O:21][c:22]3[cH:23][cH:24][n:25][c:26]4[cH:27][c:28]([O:34][CH2:35][CH:36]5[O:37][CH2:38]5)[c:29]([C:32]#[N:33])[cH:30][c:31]34)[cH:39][cH:40]2)[cH:11][cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-6cf2dc07666e49bc87f84cd30f3417f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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