Dichloromethane → 2-chloro-N-(2,4-dimethoxybenzyl)-N-[2-(3-fluorobenzoyl)-4-methoxyphenyl]acetamide

HRID 2349506Notes

Reaction equation

HRID 2349506 reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:5][NH:6][c:7]2[c:8]([C:15](=[O:16])[c:17]3[cH:18][c:19]([F:23])[cH:20][cH:21][cH:22]3)[cH:9][c:10]([O:13][CH3:14])[cH:11][cH:12]2)[cH:24][cH:25][c:26]([O:28][CH3:29])[cH:27]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl:37][CH2:38][C:39](=[O:40])[Cl:41].[Cl:42][CH2:43][Cl:44]>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][N:6]([c:7]2[c:8]([C:15](=[O:16])[c:17]3[cH:18][c:19]([F:23])[cH:20][cH:21][cH:22]3)[cH:9][c:10]([O:13][CH3:14])[cH:11][cH:12]2)[C:39]([CH2:38][Cl:37])=[O:40])[cH:24][cH:25][c:26]([O:28][CH3:29])[cH:27]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6577Chloroacetyl chlorideHCID 8471TriethylamineHCID 68659721{2-[(2,4-Dimethoxybenzyl)amino]-5-methoxyphenyl}(3-fluorophenyl)methanone

Product 1

HCID 687184392-chloro-N-(2,4-dimethoxybenzyl)-N-[2-(3-fluorobenzoyl)-4-methoxyphenyl]acetamide

Sources & evidence

ORD record
ord-73154697ee5c47fbbb055fcf3ca1df6b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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