Dichloromethane → 2-cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (1-methanesulfonyl-pyrrolidin-3-yl)-amide
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH:7]([NH:10][C:11](=[O:12])[c:13]2[cH:14][n:15]([CH2:25][O:26][CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[c:16]3[n:17][cH:18][c:19]([CH:22]4[CH2:23][CH2:24]4)[n:20][c:21]23)[CH2:8][CH2:9]1.[Cl:40][CH2:41][Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH:7]([NH:10][C:11](=[O:12])[c:13]2[cH:14][nH:15][c:16]3[n:17][cH:18][c:19]([CH:22]4[CH2:23][CH2:24]4)[n:20][c:21]23)[CH2:8][CH2:9]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f4edea20497b4f7bb3c1d82ccf0e6657
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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