Bicarbonate Ion → 3-(Trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one
Reaction equation
[C:23](=[O:24])([OH:25])[O-:26].[Cl:28][CH2:29][Cl:30].[F:31][C:32]([F:33])([F:34])[C:35]([OH:36])=[O:37].[Na+:27].[O:1]=[C:2]1[c:3]2[cH:4][c:5]([C:19]([F:20])([F:21])[F:22])[cH:6][n:7][c:8]2[CH2:9][CH2:10][N:11]1[C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18]>>[O:1]=[C:2]1[c:3]2[cH:4][c:5]([C:19]([F:20])([F:21])[F:22])[cH:6][n:7][c:8]2[CH2:9][CH2:10][NH:11]1Participants
6
Sources & evidence
- ORD record
- ord-4485d4cc24e042b987d30ddb2999102d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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