Hydrochloric Acid → 1-((2-(5-Bromo-3-(4-fluorophenoxy)pyridin-2-ylamino)thiazol-4-yl)methyl)piperazin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([O:29][c:30]2[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]2)[c:5]([NH:8][c:9]2[s:10][cH:11][c:12]([CH2:14][N:15]3[C:16](=[O:28])[CH2:17][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:19][CH2:20]3)[n:13]2)[n:6][cH:7]1.[Cl:44][CH2:45][Cl:46].[ClH:37].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[Br:1][c:2]1[cH:3][c:4]([O:29][c:30]2[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]2)[c:5]([NH:8][c:9]2[s:10][cH:11][c:12]([CH2:14][N:15]3[C:16](=[O:28])[CH2:17][NH:18][CH2:19][CH2:20]3)[n:13]2)[n:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b7641f3525fc455384d4436b36f5dd53
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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