Dimethyl Sulfoxide → N-Boc-pyrrolidine

HRID 2350209Notes

Reaction equation

HRID 2350209 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][CH2:11][CH2:12][OH:13].[CH3:14][OH:15].[CH3:16][S:17]([CH3:18])=[O:19].[Cl:20][CH2:21][Cl:22]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 887MethanolHCID 6344DichloromethaneHCID 545141tert-Butyl N-(4-hydroxybutyl)carbamate

Product 1

HCID 643455N-Boc-pyrrolidine

Sources & evidence

ORD record
ord-53ee4c54044f4c6f874c084561b595cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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