Trifluoroacetic acid → 2-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine

HRID 2350252Notes

Reaction equation

HRID 2350252 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([CH3:24])[n:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[cH:12][cH:13]1)([CH3:5])([CH3:6])[CH3:25].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH2:7][c:8]1[c:9]([CH3:24])[n:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[cH:12][cH:13]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67072248[2-Methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-carbamic acid tert-butyl ester

Product 1

HCID 219358322-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine

Sources & evidence

ORD record
ord-3d57e6cda5c04d02977b599ce8503fa0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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