Methanol → 6-(3-Acetylamino-1-pyrrolidinyl)-2-(2,4-difluorophenylamino)-5-fluoronicotinic acid
Reaction equation
[C:4]([CH3:5])(=[O:6])[NH:7][CH:8]1[CH2:9][N:10]([c:13]2[n:14][c:15]([NH:24][c:25]3[c:26]([F:32])[cH:27][c:28]([F:31])[cH:29][cH:30]3)[c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][c:22]2[F:23])[CH2:11][CH2:12]1.[CH3:1][OH:2].[Na+:34].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[OH-:33].[OH2:3]>>[C:4]([CH3:5])(=[O:6])[NH:7][CH:8]1[CH2:9][N:10]([c:13]2[n:14][c:15]([NH:24][c:25]3[c:26]([F:32])[cH:27][c:28]([F:31])[cH:29][cH:30]3)[c:16]([C:17](=[O:18])[OH:19])[cH:21][c:22]2[F:23])[CH2:11][CH2:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c8eb806572314e8ab284c47367eece52
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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