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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2350530Generated: October 25, 2026

Hydrochloric Acid → N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(pyrrolidin-1-yl)ethoxy]quinazolin-4-amine

https://huagongshe.com/reaction/2350530

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant1-(2-Chloroethyl)pyrrolidineHCID 81669—
Reactant4-(4-Chloro-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazolineHCID 135513720—
ProductN-(4-chloro-2-fluorophenyl)-6-methoxy-7-[2-(pyrrolidin-1-yl)ethoxy]quinazolin-4-amineHCID 5329018—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-43de2696027c4a44990423705309ef8c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)