Pyrrolidine → 2'-Methyl-5'-[(2-pyrrolidin-1-ylisonicotinoyl)amino]-1,1'-biphenyl-4-carboxylic acid

HRID 2350748Notes

Reaction equation

HRID 2350748 reaction equation
[CH2:27]1[CH2:28][CH2:29][NH:30][CH2:31]1.[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][cH:10][c:11]([CH3:23])[c:12](-[c:14]3[cH:15][cH:16][c:17]([C:20](=[O:21])[OH:22])[cH:18][cH:19]3)[cH:13]2)[cH:24][cH:25][n:26]1>>[c:2]1([N:30]2[CH2:29][CH2:28][CH2:27][CH2:31]2)[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][cH:10][c:11]([CH3:23])[c:12](-[c:14]3[cH:15][cH:16][c:17]([C:20](=[O:21])[OH:22])[cH:18][cH:19]3)[cH:13]2)[cH:24][cH:25][n:26]1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 210905805'-[(2-Chloroisonicotinoyl)amino]-2'-methyl-1,1'-biphenyl-4-carboxylic acid

Product 1

HCID 113501482'-Methyl-5'-[(2-pyrrolidin-1-ylisonicotinoyl)amino]-1,1'-biphenyl-4-carboxylic acid

Sources & evidence

ORD record
ord-747bf416d9a443e6b471436181319dc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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