2-Aminopyridine → HCID 53667792, compound

HRID 2350942Notes

Reaction equation

HRID 2350942 reaction equation
NC1C=CC=CN=1.[OH:8][C:9]1[C:10]([NH2:15])=[N:11][CH:12]=[CH:13][CH:14]=1.[CH2:16]([N:20]([CH2:25][CH2:26][CH2:27][O:28][C:29]1[CH:45]=[CH:44][C:32]([C:33]([C:35]2N=C3C=CC=CN3[CH:43]=2)=[O:34])=[CH:31][CH:30]=1)[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:17][CH2:18][CH3:19]>>[CH2:16]([N:20]([CH2:25][CH2:26][CH2:27][O:28][C:29]1[CH:30]=[CH:31][C:32]([C:33]([C:35]2[N:15]=[C:10]3[C:9]([OH:8])=[CH:14][CH:13]=[CH:12][N:11]3[CH:43]=2)=[O:34])=[CH:44][CH:45]=1)[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:17][CH2:18][CH3:19]

Participants

4

Reactant 3

HCID 104392-AminopyridineHCID 281142-Amino-3-HydroxypyridineHCID 54373178HCID 54373178, compound

Product 1

HCID 53667792HCID 53667792, compound

Procedure

When in the above procedure, 2-aminopyridine or 3-hydroxy-2-aminopyridine is used in place of 5-bromo-2-aminopyridine, 2-(4-dibutylaminopropoxybenzoyl)imidazo[1,2-a]pyridine or 2-(4-dibutylaminopropoxybenzoyl)-8-hydroxyimidazo[1,2-a]pyridine is obtained.

Sources & evidence

ORD record
ord-fb2df3b074d5463caf6aa1e1c047d096
Source dataset
uspto-grants-1989_10
Patent number
US04871745

Reaction notes

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