HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Aminotetrahydro-2(1H)-pyrimidinone, monohydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tetrahydro-3-[(phenylmethylene)amino]-2(1H)-pyrimidinone | HCID 54495459 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Aminotetrahydro-2(1H)-pyrimidinone, monohydrochloride | HCID 131716145 | — |
Reaction Steps
A solution of 5.7 g (28.0 mmol) tetrahydro-3-[(phenylmethylene)amino]-2(1H)-pyrimidinone in a mixture of 43 ml water and 43 ml concentrated hydrochloric acid was steam distilled until no additional benzaldehyde condensed. The residual solution was evaporated to dryness, triturated with ethanol and dried in vacuo. Yield 3.07 g, melting point 210°-215° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04871841 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-caccab3206fb436cb5c4f7d5a2a67b1d |
| Source note | uspto-grants-1989_10 |