反应详情

A solution of 5.7 g (28.0 mmol) tetrahydro-3-[(phenylmethylene)amino]-2(1H)-pyrimidinone in a mixture of 43 ml water and 43 ml concentrated hydrochloric acid was steam distilled until no additional benzaldehyde condensed. The residual solution was evaporated to dryness, triturated with ethanol and dried in vacuo. Yield 3.07 g, melting point 210°-215° C.

1. distillationdistilled until no additional benzaldehyde condensed
2. customThe residual solution was evaporated to dryness
3. customtriturated with ethanol
4. customdried in vacuo