Tetrahydrofuran → HCID 53652916, compound

Participants

Reaction Steps

Alternatively, the title compound was prepared by stirring a solution of 2-ethoxy-5-propenyl-4H-3,1-benzoxazin-4-one in THF (5 ml) and 2% sodium hydroxide (5 ml) for 6 hours. The organic solvent was removed by evaporation. The aqueous solution was acidified to pH=2 with dropwise addition of 6 M HCl. The solution was extracted with ethyl acetate and the organic was dried (magnesium sulphate) and evaporated to give an oil.

Provenance & Evidence