Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178477294 | HCID 178477294 | — |
| Product | HCID 14421557 | HCID 14421557 | — |
Reaction Steps
1-[2-Hydroxy-2-(4-ethylthio-3-methylpyrid-2-yl)ethyl]-2-mercaptobenzimidazole (0.01 mole) is dissolved in polyphosphoric acid (10 g) and the mixture heated at 100° C. for 2 hours with stirring. The mixture is then neutralised with sodium hydroxide solution and the product extracted with chloroform. Purification by column chromatography on silica gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04873237 |
|---|
| Source dataset | uspto-grants-1989_10 |
|---|
| ORD ID | ord-c7efd7455ddb4443b31c72b896ed574e |
|---|
| Source note | uspto-grants-1989_10 |
|---|
