m-Chloroperbenzoic acid → HCID 14421558, compound

HRID 2351304Notes

Reaction equation

HRID 2351304 reaction equation
[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([CH:10]2[S:21][C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH2:11]2)[C:5]=1[CH3:22])[CH3:2].ClC1C=C(C=CC=1)C(OO)=[O:28]>C(Cl)Cl>[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([CH:10]2[S:21](=[O:28])[C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH2:11]2)[C:5]=1[CH3:22])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 14421557HCID 14421557, compound

Product 1

HCID 14421558HCID 14421558, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 2-(4-ethylthio-3-methylpyrid-2-yl)-2,3-dihydrothiazolo[3,2-a]benzimidazole (0.01 mole) is dissolved in CH2Cl2 solution (100 ml) at 0° C. and treated with m-chloroperoxybenzoic acid (0.01 mole) for 0.5 hours. The solution is then washed with sodium carbonate solution and dried (MgSO4). Purification by chromatography on silica gives the title compound.

Workup

  1. washThe solution is then washed with sodium carbonate solution
  2. dry with materialdried (MgSO4)
  3. customPurification by chromatography on silica

Sources & evidence

ORD record
ord-fd9d4e6373c14ccdaadc33f5c7671d08
Source dataset
uspto-grants-1989_10
Patent number
US04873237

Reaction notes

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