Ammonium Hydroxide → HCID 14183123, compound

HRID 2351344Notes

Reaction equation

HRID 2351344 reaction equation
[SH:1][C:2]1[S:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[CH:8]=2)[N:3]=1.[O-]Cl.[Na+].[OH-].[NH4+:19]>[OH-].[Na+].O>[CH3:14][O:13][C:9]1[CH:8]=[C:7]([C:4]2[N:3]=[C:2]([S:1][NH2:19])[S:6][N:5]=2)[CH:12]=[CH:11][CH:10]=1

Participants

6

Reactant 3

HCID 14923Ammonium HydroxideHCID 23665760Sodium HypochloriteHCID 178489945HCID 178489945, compound

Product 1

HCID 14183123HCID 14183123, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 14798Sodium HydroxideSolvent

Procedure

A solution of 2.2 g of 5-mercapto-3-(3-methoxyphenyl)-1,2,4-thiadiazole in 35 ml of 5% sodium hydroxide and a solution prepared by diluting 22 ml of 5.25% NaOCl solution to 35 ml with water were added dropwise simultaneously to 95 ml of ammonium hydroxide solution while maintaining the mixture at 0°. The resulting mixture was stirred for 15 minutes and the precipitated solid was collected, washed with water and dried (P2O5 /high vacuum) to give 1.76 l g of solid, m.p. 157°-160° C.

Workup

  1. temperaturewhile maintaining the mixture at 0°
  2. customthe precipitated solid was collected
  3. washwashed with water
  4. dry with materialdried (P2O5 /high vacuum)
  5. customto give 1.76 l g of solid, m.p. 157°-160° C.

Sources & evidence

ORD record
ord-59af8ae7a09f4e4b80ae5d8fd8ef95b1
Source dataset
uspto-grants-1989_10
Patent number
US04873239

Reaction notes

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