Ammonium Hydroxide → HCID 14183093, compound

HRID 2351345Notes

Reaction equation

HRID 2351345 reaction equation
[SH:1][C:2]1[S:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][CH:8]=2)[N:3]=1.[O-]Cl.[Na+].[OH-].[NH4+:19]>[OH-].[Na+].O>[CH3:14][O:13][C:10]1[CH:11]=[CH:12][C:7]([C:4]2[N:3]=[C:2]([S:1][NH2:19])[S:6][N:5]=2)=[CH:8][CH:9]=1

Participants

6

Reactant 3

HCID 14923Ammonium HydroxideHCID 23665760Sodium HypochloriteHCID 178489179HCID 178489179, compound

Product 1

HCID 14183093HCID 14183093, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 14798Sodium HydroxideSolvent

Procedure

A solution of 25 g of 5-mercapto-3-(4-methoxyphenyl)-1,2,4-thiadiazole in 350 ml of 5% sodium hydroxide and a solution prepared by diluting 220 ml of 5.25% NaOCl to 350 ml with water were added simultaneously to 950 ml of ammonium hydroxide solution while maintaining the mixture at 0°. The resulting mixture was stirred for 15 minutes and the precipitated solid was collected, washed with water and dried (P2O5 /high vacuum) to give 15.6 g of solid, m.p. 136°-139°.

Workup

  1. temperaturewhile maintaining the mixture at 0°
  2. customthe precipitated solid was collected
  3. washwashed with water
  4. dry with materialdried (P2O5 /high vacuum)

Sources & evidence

ORD record
ord-5127f4c884b144c6af2b29cf37fc2406
Source dataset
uspto-grants-1989_10
Patent number
US04873239

Reaction notes

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