反应详情

A mixture of 3 g of 3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide and 11 ml of triethyl orthoacetate was warmed to reflux for 3.5 hours. The mixture was cooled, triturated with hexane (25 ml) and filtered to give 3.13 g of solid, m.p. 70°-72° C.

1. temperaturewas warmed
2. temperatureto reflux for 3.5 hours
3. temperatureThe mixture was cooled
4. customtriturated with hexane (25 ml)
5. filtrationfiltered