HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl orthoacetate → N-(1-Ethoxyethylidene)-3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl orthoacetate | HCID 66221 | — |
| Reactant | 3-(2-Chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide | HCID 14183136 | — |
| Product | N-(1-Ethoxyethylidene)-3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide | HCID 53969492 | — |
Reaction Steps
A mixture of 3 g of 3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide and 11 ml of triethyl orthoacetate was warmed to reflux for 3.5 hours. The mixture was cooled, triturated with hexane (25 ml) and filtered to give 3.13 g of solid, m.p. 70°-72° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873239 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-ca968de37642459baecb021898ec295c |
| Source note | uspto-grants-1989_10 |