HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → 4-[2-[(Diethylamino)methyl]-piperidin-1-yl]butane nitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | (+/-)-2-[2-[(Dipropylamino)methyl]piperidin-1-yl]acetonitrile | HCID 10490074 | — |
| Reactant | N-(Piperidin-2-ylmethyl)-N-propylpropan-1-amine | HCID 10798040 | — |
| Solvent | Dichloromethane ethylacetate | HCID 21226138 | — |
| Product | 4-[2-[(Diethylamino)methyl]-piperidin-1-yl]butane nitrile | HCID 19845965 | — |
Reaction Steps
from 2-[(dipropylamino)methyl]piperidine and 2-bromoacetonitrile, (±)-2-[2-[(dipropylamino)methyl]piperidin-1-yl]acetonitrile, RF 0.9 (Macherey-Nagel, PolygramRSIL G/UV254, pre-coated plastic sheets for TLC, eluant: dichloromethane/ethyl acetate 50:50 v/v).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873236 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-86fbff9b1c5a4f72bcb9803d828abca4 |
| Source note | uspto-grants-1989_10 |